Our older one, the one that's been with us the shorter time, wasn't so lucky. Her feet started swelling up so we got her in to the vet. Bacterial infection. We started injections every two days for it. It started getting better. She started growing again, had a shed, then her feet started swelling again.
Back to the doc she went. Turns out we'd knocked back the original bacteria, but she'd picked up another one during her shed. So, a new drug, this one oral, every day dosing. She started healing, started growing again, had a shed, and appeared to be OK. Until a couple days ago. Feet started swelling yet again. Now her chest is starting to swell up along the sides.

The worst part of this is we have no idea how old she actually is. We got her from my brother-in-law, who had gotten her from a friend who had gotten her from a friend. Essentially, we're so far removed from point of origin that we don't know much about her history other than brother-in-law went through a neglectful period before we got ahold of her and we received her in pretty rough shape. Parasites, infections, you name it. We'd nursed her back to health and she's had several years of stomping the shit out of crickets and worms since until this came up.
The past week or so Gecko #1 has been standing protectively over Gecko #2 in one of their shared hides in the back of their palace anytime she's not hunting. She won't let anybody near her but me. If the wife reaches too close she gets bit. That's not normally Gecko #1's personality at all. She's friendly with everybody but the cats most of the time.
In amongst all the other life drama right now (mom in mental ward/shock treatments, her husband going into depression right when she needs him most, whole family going batshit over this mess, things going completely mental at work, a dog recovering from a torn ACL repair surgery, several other unmentionables) this is getting to me a bit. I hate it when the animals aren't healthy and we can't seem to do the right thing to help them out in a timely fashion.
It may seem silly to those of you that don't have any connection to our cold blooded bretheren, but she's a part of the family.
And it's easier to focus on this than the shit I literally CAN'T do anything about at the moment.